When injected into one of the cavities, a silver or glass syringe should be preferred. For application to an ulcer on the cornea, I have usually employed a fine-pointed camel's-hair pencil, which is first moistened, and then rubbed upon a piece of the nitrate, so as to make a saturated solution at the point, which is gently applied to the little ulcer. Any mechanical injury from the hard-pointed stick is thus avoided. in the treatment of Psorophthalmia, the same measure may be employed. Remove mechanically the crusts formed at the root of the eyelashes, and then touch the diseased points with the extremity of the hair pencil. To the thickened palpebral conjunctiva, as also to the os uteri and vagina, the stick may be applied with safety when required; but, in the former ease, care should be taken to remove any superfluous nitrate. To narrow fistulous sores, of a callous character, it may be advantageously applied by first dipping a silver probe into nitric acid, which forms a nitrate on the surface, and then introducing it into the ulcer. in all cases, after the application of the caustic, the superfluous nitrate may be removed, when requisite, by washing the surface with a solution of common salt.

An aqueous solution of various strength has been used, by subcutaneous injection, with great advantage, by Dr. Luton, of Rheims, with a view to its substitutive effect, in obstinate neuralgia, especially sciatica. A phlegmon with suppuration follows; but no harm results, as the inflammation has very little tendency to diffusion. He uses from five to twenty drops of a solution containing one-tenth of the nitrate. (Arch. Gén., 6e ser, II. 387.)

An ointment has been used in erysipelatous inflammation, and some other external affections, made with one or two parts of the finely powdered nitrate to four parts of lard, which, applied twice a day to the inflamed surface, produces severe pain, with vesication, but is said to extinguish or arrest the erysipelas.

Finally, this salt has been used by inhalation, either in a state of impalpable powder, mixed with an equal weight of lycopodium, or in solution in the state of spray, by means of the atomizer, with supposed advantage, in laryngeal and bronchial inflammation and ulceration. (Cornell, Bost. Med. and Surg. Journ., Sept. 25, 1850.) Dr. Ebert, of Berlin, recommends the powder in all laryngeal mucous inflammations. He mixes three grains of the nitrate with a drachm of sugar, which he puts into a steel pen, firmly inserted in a quill open at both ends. One end of the instrument is introduced into the mouth so that the point of the steel pen lies over the root of the tongue. The patient then closes his mouth, and inspires strongly through the tube. The first trial generally fails, but the patient succeeds at last. A little cough and irritation follow, but without any considerable pain. (Ed. Med. Journ., July, 1855, p. 54.)

For inhalation in the form of spray, a solution of the nitrate is used containing from one to ten grains to a fluidounce of distilled water. in this form, the remedy has been employed especially in ulceration of the pharynx and larynx, and in follicular laryngitis. Care must always be taken to guard the face by means of a mask, in order to prevent discoloration of the skin.